Endometrial Cancer

What is Endometrial Cancer?

  • Endometrial cancer starts when cells in the inner lining of the uterus (endometrium) begin to grow out of control. Cells in nearly any part of the body can become cancerous and spread to other areas of the body.

https://www.google.co.in/url?sa=t&rct=j&q=&esrc=s&source=web&cd=1&cad=rja&uact=8&ved=0ahUKEwjfzbOc77PNAhXMMY8KHQFFAO0QFggbMAA&url=http%3A%2F%2Fwww.cancer.org%2Fcancer%2Fendometrialcancer%2Fdetailedguide%2Fendometrialuterine-cancer-what-is-endometrialcancer&usg=AFQjCNEBsyTTzRWeGnL9jHc2ABKruRzdrQ&sig2=agyVxr_fiCqUSvXCWxK6Ug

What Causes Endometrial Cancer?

  • Things that affect hormone levels, like taking estrogen after menopause, birth control pills, or tamoxifen; the number of menstrual cycles (over a lifetime), pregnancy, obesity, certain ovarian tumours, and polycystic ovarian syndrome
  • Use of an intrauterine device
  • Advanced age
  • Poor diet and lack of exercise
  • Diabetes
  • Family history (having close relatives with endometrial or colorectal cancer)
  • Having been diagnosed with breast or ovarian cancer in the past
  • Having been diagnosed with endometrial hyperplasia in the past
  • Treatment with radiation therapy to the pelvis to treat another cancer

https://www.google.co.in/url?sa=t&rct=j&q=&esrc=s&source=web&cd=1&cad=rja&uact=8&ved=0ahUKEwjN6tD38rPNAhXIqI8KHT4QCUQFggbMAA&url=http%3A%2F%2Fwww.cancer.org%2Fcancer%2Fendometrialcancer%2Fdetailedguide%2Fendometrial-uterine-cancer-whatcauses&usg=AFQjCNF5sWtmLjKNicU4HJGI7AGK3WRT_Q&sig2=f5UqC41nn3ADgLOY8raJPg

Symptoms of Endometrial Cancer

Signs and symptoms of endometrial cancer may include:

  • Vaginal bleeding after menopause
  • Bleeding between periods
  • An abnormal, watery or blood-tinged discharge from your vagina
  • Pelvic pain

https://www.google.co.in/url?sa=t&rct=j&q=&esrc=s&source=web&cd=13&cad=rja&uact=8&ved=0ahUKEwiN0d6Z8rPNAhWIPI8KHXoOD2cQFghRMAw&url=http%3A%2F%2Fwww.mayoclinic.org%2Fdiseases-conditions%2Fendometrial-cancer%2Fsymptomscauses%2Fdxc-20205706&usg=AFQjCNHWpHxf1hjeCitNj_n3z1Ini8RBrg&sig2=K3sWMNB_SmOnAlPPLIr8tA

Treatment of Endometrial Cancer

After all of the test results have been reviewed, your doctor will recommend one or more
treatment options. The four basic types of treatment for women with endometrial cancer are:

  • Surgery
  • Radiation therapy
  • Hormonal therapy
  • Chemotherapy

Surgery is the main treatment for most women with this cancer. However, in certain
situations, a combination of these treatments may be used. The choice of treatment depends
largely on the type of cancer and stage of the disease when it is found.

https://www.google.co.in/url?sa=t&rct=j&q=&esrc=s&source=web&cd=4&cad=rja&uact=8&ved=0ahUKEwj0383A9LPNAhVGo48KHcpYBhkQFggxMAM&url=http%3A%2F%2Fwww.cancer.org%2Fcancer%2Fendometrialcancer%2Fdetailedguide%2Fendometrial-uterinecancer-treating-generalinfo&usg=AFQjCNExhnKUwdVYntaW0IusmQFgx63_aA&sig2=_pYalaOVpznZ8M8vm9ywtw

Links to Endometrial Cancer Studies

  • Hormone replacement therapy and endometrial cancer risk: A meta-analysis

http://scholar.google.co.in/scholar_url?url=http://www.sciencedirect.com/science/article/pii/002978449400383O&hl=en&sa=X&scisig=AAGBfm136iOCxNGmQl9HR1mVOr95ku0pBA&nossl=1&oi=scholarr&ved=0ahUKEwiWzOL79bPNAhWGso8KHSQaBbIQgAMIGigAMAA

  • Endometrial Cancer in Tamoxifen-Treated Breast Cancer Patients: Findings From the
    National Surgical Adjuvant Breast and Bowel Project (NSABP) B-14

http://scholar.google.co.in/scholar_url?url=http://jnci.oxfordjournals.org/content/86/7/527.short&hl=en&sa=X&scisig=AAGBfm38kxrxPTo8JEb9oRsgKGQXfEVomA&nossl=1&oi=scholarr&ved=0ahUKEwiWzOL79bPNAhWGso8KHSQaBbIQgAMIHCgCMAA